EI Mechanisms- Wahrhaftig Diagrams

This lecture (5/9/05) continues our look at detailed EI fragmentation mechanisms, in particular discussing the importance and creation of Wahrhaftig diagrams. The coverage is generally from Chapter 7 of McLafferty's book, Interpretation of Mass Spectra, 4th ed.

Wahrhaftig Diagrams mp3 podcast Right-click and select "save target as" if downloading manually.

EI Fragmentation Mechanisms

This lecture (5/2/05) begins our look at detailed EI mechanisms. The coverage is generally from Chapter 7 of McLafferty's book, Interpretation of Mass Spectra, 4th ed.

EI mechanisms mp3 podcast Right-click and select "save target as" if downloading manually.

MS Spectra Interpretation 3

This lecture (4/25/05) continues our look at EI mass spectra and how to apply our interpretation strategies on real MS data (obtained from the NIST 98 library). The NIST 98 library available so we can compare the spectra for each of our proposed structures.

MS Spectral Interpretation 3 mp3 podcast Right-click and select "save target as" if downloading manually.

MS Spectra interpretation 2

This lecture (4/20/05) continues our look at EI mass spectra and how to apply our interpretation strategies on real MS data (obtained from the NIST 98 library). The NIST 98 library available so we can compare the spectra for each of our proposed structures.

MS Spectral Interpretation 2 mp3 podcast Right-click and select "save target as" if downloading manually.

MS Spectral Interpretation 1

This lecture (4/18/05) finishes the discussion of EI interpretation strategies. We then move on to look at EI mass spectra and see how to apply these strategies on real MS data (obtained from the NIST 98 library).

MS Spectral Interpretation 1 mp3 podcast Right-click and select "save target as" if downloading manually.

MS Interpretation 2 lecture

This lecture (4/13/05) continues the discussion of EI interpretation strategies. It includes a discussion of how the pressure in the ion source determines whether the fragmentation processes we observed are unimolecular in nature.

MS Interpretation 2 mp3 podcast Right-click and select "save target as" if downloading manually.

MS Interpretation 1 lecture

This lecture (4/11/05) starts covering issues related to the interpretation of EI mass spectra- including how to to identify the molecular ion in a mass spectrum.

MS Interpretation 1 mp3 podcast Right-click and select "save target as" if downloading manually.

MS Comparison Lecture

This lecture (4/6/05) is a brief introduction to the various types of mass spectrometers available. This will allow you to understand the range of capabilities available. At the end we use a simple magnetic sector instrument as an example of how we various instrument parameters affect the masses observed in the spectrum.

MS Comparison mp3 podcast Right-click and select "save target as" if downloading manually.

Isotopes lecture

This lecture (4/4/05) covers isotopes- what they are, how to find mass and abundance information on the NIST website, how to calculate isotope patterns (using tools freely available on the web), and how they are used to assist in spectral interpretation in mass spectrometry.

Isotopes mp3 podcast Right-click and select "save target as" if downloading manually.

Welcome

Welcome to the blog for the course CHEM755 Mass Spectrometry, a graduate analytical core-sequence course in the Chemistry Department at Drexel University, Philadelphia, PA. This course is running during the spring quarter 2004/2005 (March 28 thru June 6 2005).

PodCast Instructions

You can now receive the lecture audio mp3's for this class automatically through the RSS feed for the class.

You must first download an aggregator that handles files like ipodder.

First click on the XML button on the top of the class page.
Then copy the url that shows up in the address bar and paste it in under the subscriptions tab in ipodder.

Ipodder will automatically download mp3's as they become available. On your PC these files will show up in a folder called "My Received Podcasts" under "My Documents". I believe that if you have an ipod it will copy the files directly onto the device.

The nice thing is that the downloads happen in the background, as long as you are connected to the internet. Let me know how it works out.